Charlotte Ellen Dean was introduced to cricket by her father, who played cricket for Staffordshire and Warwickshire. The off-break bowler took five wickets on her debut for Portsmouth Grammar School in 2017 and captained Hampshire U-15s to victory in the Royal London County Cup. In August 2021, Dean was named in England's WT20I squad for their series against New Zealand. However, Dean was ruled out of the first WT20I match after being identified as a possible COVID-19 contact. The following month, Dean was named in England's WODI squad. She made her WODI debut on 16 September 2021 against New Zealand and went on to be the joint-leading wicket-taker in the five-match series, with 10 wickets. It included a 4/36 in the 2nd ODI to help England to a 13-run victory. In December 2021, Dean was named in England's squad for their tour to Australia to contest the Women's Ashes. She made her WT20I debut on 22 January 2022 against Australia and her Test match debut on 27 January 2022 for England against Australia in the one-off Women's Ashes Test. She dismissed Beth Mooney to claim her first Test wicket and ended with figures of 2/24 in Australia's second innings. In February 2022, she was named in England's squad for the 2022 Women's Cricket World Cup in New Zealand. Year 2022 was when she firmly stamped her authority as a mainstay in England’s white-ball attack. The December tour of the West Indies became her personal showcase, a series where her evolving craft as an off-spinner took centre stage. Dean led the bowling charts in both formats, collecting seven wickets in the ODIs and a staggering eleven in the T20Is. Her ability to read batters, vary her pace, and hold her nerve in crucial phases transformed her into a go-to weapon for England. Crowned Player of the Series in the T20Is, Dean’s performances weren’t just statistically dominant—they exuded tactical maturity, control, and a quiet confidence that belied her age. The global stage awaited, and Charlie De